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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2507
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Dmd
Name: dystrophin
Acc ID: CHEBI:28748
Term: doxorubicin
Definition: An anthracycline antibiotic that has formula C27H29NO11.
Chemical ID: MESH:D004317
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Dmddecreases expressionISODMD (Homo sapiens)6480464CTDDoxorubicin results in decreased expression of DMD mRNAPMID:26537877 PMID:28940058 PMID:29803840
Dmdmultiple interactionsISODmd (Mus musculus)6480464CTDDMD protein affects the reaction [Doxorubicin results in decreased expression of ACTA1 mRNA]; DMD protein affects the reaction [Doxorubicin results in decreased expression of BDH1 mRNA]; DMD protein affects the reaction [Doxorubicin results in decreased expression of BGN mRNA]; DMD protein affects the reaction [Doxorubicin results in decreased expression of HSPH1 mRNA]; DMD protein affects the reaction [Doxorubicin results in decreased expression of POSTN mRNA]; DMD protein affects the reaction [Doxorubicin results in decreased expression of SPP1 mRNA]; DMD protein affects the reaction [Doxorubicin results in increased expression of DSC2 mRNA]; DMD protein affects the reaction [Doxorubicin results in increased expression of MYL7 mRNA]; DMD protein affects the reaction [Doxorubicin results in increased expression of SPSB1 mRNA]PMID:17888722
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