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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2206
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bglap
Name: bone gamma-carboxyglutamate protein
Acc ID: CHEBI:28741
Term: sodium fluoride
Definition: A metal fluoride salt with a Na(+) counterion.
Chemical ID: MESH:D012969
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Bglapaffects expressionEXP 6480464CTDSodium Fluoride affects the expression of BGLAP mRNAPMID:25132241
Bglapdecreases expressionISOBGLAP (Homo sapiens)6480464CTDSodium Fluoride results in decreased expression of BGLAP mRNAPMID:26339601
Bglapincreases expressionISOBglap (Mus musculus)6480464CTDSodium Fluoride results in increased expression of BGLAP mRNA; Sodium Fluoride results in increased expression of BGLAP proteinPMID:35218729
Bglapincreases expressionISOBGLAP (Homo sapiens)6480464CTDSodium Fluoride results in increased expression of BGLAP proteinPMID:30259626 PMID:34942272
Bglapmultiple interactionsISOBglap (Mus musculus)6480464CTDBMP2 protein affects the reaction [Sodium Fluoride results in increased expression of BGLAP mRNA]; BMP2 protein affects the reaction [Sodium Fluoride results in increased expression of BGLAP protein]; CTNNB1 protein affects the reaction [BMP2 protein affects the reaction [Sodium Fluoride results in increased expression of BGLAP mRNA]]; CTNNB1 protein affects the reaction [BMP2 protein affects the reaction [Sodium Fluoride results in increased expression of BGLAP protein]]PMID:35218729
Bglapmultiple interactionsISOBGLAP (Homo sapiens)6480464CTDMIR21 mRNA affects the reaction [Sodium Fluoride results in increased expression of BGLAP protein]PMID:34942272
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