GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Psen1 | increases uptake | ISO | PSEN1 (Homo sapiens) | 6480464 | CTD | PSEN1 protein results in increased uptake of Copper | PMID:21239495 | Psen1 | increases uptake | ISO | Psen1 (Mus musculus) | 6480464 | CTD | PSEN1 protein results in increased uptake of Copper | PMID:21239495 | Psen1 | multiple interactions | ISO | Psen1 (Mus musculus) | 6480464 | CTD | [APP gene mutant form co-treated with PSEN1 gene mutant form] results in increased abundance of Copper; Copper promotes the reaction [[PSEN1 gene mutant form co-treated with APP gene mutant form co-treated with MAPT gene mutant form] results in decreased expression of CPLX1 protein]; Copper promotes the reaction [[PSEN1 gene mutant form co-treated with APP gene mutant form co-treated with MAPT gene mutant form] results in decreased expression of CPLX2 protein] | PMID:23541064 PMID:25352456 | |
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