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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620573
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyba
Name: cytochrome b-245 alpha chain
Acc ID: CHEBI:28689
Term: dehydroepiandrosterone
Definition: An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.
Chemical ID: MESH:D003687
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cybaincreases expressionEXP 6480464CTDDehydroepiandrosterone results in increased expression of CYBA mRNA; Dehydroepiandrosterone results in increased expression of CYBA proteinPMID:27634381
Cybamultiple interactionsEXP 6480464CTDMetformin affects the reaction [Dehydroepiandrosterone results in increased expression of CYBA protein]; Metformin inhibits the reaction [Dehydroepiandrosterone results in increased expression of CYBA mRNA]; Quercetin affects the reaction [Dehydroepiandrosterone results in increased expression of CYBA protein]; Quercetin inhibits the reaction [Dehydroepiandrosterone results in increased expression of CYBA mRNA]PMID:27634381
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