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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 737364 Species: Homo sapiens RGD Object: Gene Symbol: PKLR Name: pyruvate kinase, liver and RBC

Acc ID: CHEBI:28593 Term: quinidine Definition: A cinchona alkaloid consisting of cinchonine with the hydrogen at the 6-position of the quinoline ring substituted by methoxy. CasRN: 56-54-2 Chemical ID: MESH:D011802

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
decreases expression	ISO	RGD:3336	6480464	CTD	Quinidine results in decreased expression of PKLR mRNA	PMID:17522070