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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2475
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp2e1
Name: cytochrome P450, family 2, subfamily e, polypeptide 1
Acc ID: CHEBI:28593
Term: quinidine
Definition: A cinchona alkaloid consisting of cinchonine with the hydrogen at the 6-position of the quinoline ring substituted by methoxy.
Chemical ID: MESH:D011802
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp2e1decreases activityISOCyp2e1 (Mus musculus)6480464CTDQuinidine results in decreased activity of CYP2E1 proteinPMID:18420780
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