GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ahr | affects binding | ISO | AHR (Homo sapiens) | 6480464 | CTD | kaempferol binds to AHR protein | PMID:17012224 | Ahr | increases activity | ISO | AHR (Homo sapiens) | 6480464 | CTD | kaempferol results in increased activity of AHR protein | PMID:19034627 | Ahr | multiple interactions | ISO | Ahr (Mus musculus) | 6480464 | CTD | kaempferol inhibits the reaction [beta-Naphthoflavone promotes the reaction [AHR protein binds to ARNT protein]]; kaempferol inhibits the reaction [beta-Naphthoflavone results in increased activity of [AHR protein binds to ARNT protein]]; kaempferol inhibits the reaction [Tetrachlorodibenzodioxin inhibits the reaction [AHR protein binds to AIP protein]]; kaempferol inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to ARNT protein]]; kaempferol inhibits the reaction [Tetrachlorodibenzodioxin results in increased localization of AHR protein] | PMID:17012224 PMID:20450880 | Ahr | multiple interactions | ISO | AHR (Homo sapiens) | 6480464 | CTD | kaempferol inhibits the reaction [Benzo(a)pyrene results in increased activity of AHR protein]; kaempferol inhibits the reaction [Tetrachlorodibenzodioxin binds to AHR protein]; kaempferol inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to CYP1A1 enhancer]]; kaempferol inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to CYP1A1 promoter]]; kaempferol inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to CYP1B1 enhancer]]; kaempferol inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to CYP1B1 promoter]]; kaempferol inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of AHR protein]; kaempferol inhibits the reaction [Tetrachlorodibenzodioxin results in increased phosphorylation of AHR protein] | PMID:10359656 PMID:14644660 PMID:17012224 PMID:19794518 PMID:20450880 PMID:20846786 | |
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