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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2202
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bdnf
Name: brain-derived neurotrophic factor
Acc ID: CHEBI:28487
Term: reserpine
Definition: An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria.
Chemical ID: MESH:D012110
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Bdnfdecreases expressionEXP 6480464CTDReserpine results in decreased expression of BDNF proteinPMID:33279466
Bdnfmultiple interactionsEXP 6480464CTDcerebrolysin inhibits the reaction [Reserpine results in decreased expression of BDNF protein]; Fluoxetine inhibits the reaction [Reserpine results in decreased expression of BDNF protein]PMID:33279466
Bdnfdecreases expressionISOBdnf (Mus musculus)6480464CTDReserpine results in decreased expression of BDNF proteinPMID:26114099
Bdnfmultiple interactionsISOBdnf (Mus musculus)6480464CTDarsenic trioxide promotes the reaction [Reserpine results in decreased expression of BDNF protein]PMID:26114099
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