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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 734280 Species: Mus musculus RGD Object: Gene Symbol: Cdk7 Name: cyclin-dependent kinase 7

Acc ID: CHEBI:28445 Term: vincristine Definition: A vinca alkaloid that has formula C46H56N4O10. CasRN: 57-22-7 Chemical ID: MESH:D014750

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
increases response to substance	ISO	RGD:734279	6480464	CTD	CDK7 gene SNP results in increased susceptibility to Vincristine	PMID:20864405