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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1552559 Species: Mus musculus RGD Object: Gene Symbol: Trpv1 Name: transient receptor potential cation channel, subfamily V, member 1

Acc ID: CHEBI:28411 Term: allicin Definition: A sulfoxide that has formula C6H10OS2. CasRN: 539-86-6 Chemical ID: MESH:C006452

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
affects response to substance	ISO	RGD:733197	6480464	CTD	TRPV1 protein affects the susceptibility to allicin	PMID:17110039
increases response to substance	ISO	RGD:733197	6480464	CTD	TRPV1 protein mutant form results in increased susceptibility to allicin	PMID:17110039