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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619991
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Vegfa
Name: vascular endothelial growth factor A
Acc ID: CHEBI:28393
Term: beta-D-glucosamine
Definition: A 2-amino-2-deoxy-D-glucopyranose that is D-glucosamine having a beta-configuration at the anomeric position.
Chemical ID: MESH:D005944
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Vegfaincreases expressionEXP 6480464CTDGlucosamine results in increased expression of VEGFA proteinPMID:16324875
Vegfadecreases expressionISOVEGFA (Homo sapiens)6480464CTDGlucosamine results in decreased expression of VEGFA proteinPMID:19254699
Vegfamultiple interactionsISOVEGFA (Homo sapiens)6480464CTDGlucosamine inhibits the reaction [Oxygen deficiency results in increased expression of VEGFA protein]PMID:19254699
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