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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3031
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Smad2
Name: SMAD family member 2
Acc ID: CHEBI:28393
Term: beta-D-glucosamine
Definition: A 2-amino-2-deoxy-D-glucopyranose that is D-glucosamine having a beta-configuration at the anomeric position.
Chemical ID: MESH:D005944
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Smad2increases phosphorylationISOSMAD2 (Homo sapiens)6480464CTDGlucosamine analog results in increased phosphorylation of SMAD2 proteinPMID:20458730
Smad2multiple interactionsISOSMAD2 (Homo sapiens)6480464CTD4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Glucosamine analog results in increased phosphorylation of SMAD2 protein]PMID:20458730
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