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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1306853 Species: Rattus norvegicus RGD Object: Gene Symbol: Traf6 Name: TNF receptor-associated factor 6, E3 ubiquitin protein ligase

Acc ID: CHEBI:28393 Term: beta-D-glucosamine Definition: A 2-amino-2-deoxy-D-glucopyranose that has formula C6H13NO5. CasRN: 3416-24-8 Chemical ID: MESH:D005944

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
multiple interactions	ISO	RGD:1315706	6480464	CTD	Glucosamine inhibits the reaction [TNF results in increased expression of TRAF6 mRNA] Glucosamine analog inhibits the reaction [TNF results in increased expression of TRAF6 mRNA]	PMID:18173918