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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731071 Species: Homo sapiens RGD Object: Gene Symbol: AHR Name: aryl hydrocarbon receptor

Acc ID: CHEBI:28262 Term: dimethyl sulfoxide Definition: A 2-carbon sulfoxide in which the sulfur atom has two methyl substituents. CasRN: 67-68-5 Chemical ID: MESH:D004121

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
multiple interactions	EXP		6480464	CTD	Dimethyl Sulfoxide promotes the reaction [AHR protein binds to CAD promoter]	PMID:16675542
decreases expression	ISO	RGD:10127	6480464	CTD	Dimethyl Sulfoxide results in decreased expression of AHR mRNA	PMID:22486318