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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2130
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Apoa1
Name: apolipoprotein A1
Acc ID: CHEBI:28262
Term: dimethyl sulfoxide
Definition: A 2-carbon sulfoxide in which the sulfur atom has two methyl substituents.
Chemical ID: MESH:D004121
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Apoa1increases activityEXP 6480464CTDDimethyl Sulfoxide results in increased activity of APOA1 promoterPMID:16423621
Apoa1increases expressionISOAPOA1 (Homo sapiens)6480464CTDDimethyl Sulfoxide results in increased expression of APOA1 mRNA; Dimethyl Sulfoxide results in increased expression of APOA1 proteinPMID:16423621
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