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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2652
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gad1
Name: glutamate decarboxylase 1
Acc ID: CHEBI:28216
Term: methylmercury chloride
Definition: A chlorine molecular entity that has formula CH3ClHg.
Chemical ID: MESH:C004925
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gad1decreases expressionISOGad1 (Mus musculus)6480464CTDmethylmercuric chloride results in decreased expression of GAD1 mRNAPMID:21385734
Gad1increases expressionISOGAD1 (Homo sapiens)6480464CTDmethylmercuric chloride results in increased expression of GAD1 mRNAPMID:23179753 PMID:26272509
Gad1multiple interactionsISOGAD1 (Homo sapiens)6480464CTD[NOG protein co-treated with methylmercuric chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GAD1 mRNAPMID:27188386
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