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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 68371
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mtor
Name: mechanistic target of rapamycin kinase
Acc ID: CHEBI:28200
Term: 2-chloroethanol
Definition: A chloroethanol carrying a chloro substituent at position 2.
Chemical ID: MESH:D005023
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mtorincreases phosphorylationISOMtor (Mus musculus)6480464CTDEthylene Chlorohydrin results in increased phosphorylation of MTOR proteinPMID:26962056
Mtormultiple interactionsISOMtor (Mus musculus)6480464CTD[Ethylene Chlorohydrin co-treated with Lipopolysaccharides] results in increased phosphorylation of MTOR protein; Sirolimus inhibits the reaction [[Ethylene Chlorohydrin co-treated with Lipopolysaccharides] results in increased phosphorylation of MTOR protein]PMID:31499194
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