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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 11275 Species: Mus musculus RGD Object: Gene Symbol: Ccl2 Name: chemokine (C-C motif) ligand 2

Acc ID: CHEBI:28177 Term: theophylline Definition: A dimethylxanthine having the two methyl groups located at positions 1 and 3. CasRN: 58-55-9 Chemical ID: MESH:D013806

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
multiple interactions	ISO	RGD:731046	6480464	CTD	[Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of CCL2 protein	PMID:18951874