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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69259 Species: Rattus norvegicus RGD Object: Gene Symbol: Axin2 Name: axin 2

Acc ID: CHEBI:28121 Term: harmine Definition: A harmala alkaloid in which the harman skeleton is methoxy-substituted at C-7. CasRN: 442-51-3 Chemical ID: MESH:D006247

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
multiple interactions	ISO	RGD:735540	6480464	CTD	Harmine inhibits the reaction [WNT3A protein results in increased expression of AXIN2 mRNA]	PMID:20519739