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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 70963
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Folh1
Name: folate hydrolase 1
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Folh1decreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in decreased expression of FOLH1 mRNAPMID:32109520
Folh1affects expressionISOFolh1 (Mus musculus)6480464CTDTetrachlorodibenzodioxin affects the expression of FOLH1 mRNAPMID:24680724
Folh1multiple interactionsISOFOLH1 (Homo sapiens)6480464CTD[Endosulfan co-treated with Tetrachlorodibenzodioxin] results in decreased expression of FOLH1 mRNAPMID:26159488
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