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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 70552
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Acsl3
Name: acyl-CoA synthetase long-chain family member 3
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Acsl3increases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in increased expression of ACSL3 mRNAPMID:21215274
Acsl3affects expressionISOAcsl3 (Mus musculus)6480464CTDTetrachlorodibenzodioxin affects the expression of ACSL3 mRNAPMID:26377647
Acsl3decreases expressionISOACSL3 (Homo sapiens)6480464CTDTetrachlorodibenzodioxin results in decreased expression of ACSL3 mRNAPMID:19684285 PMID:20106945 PMID:21632981
Acsl3decreases expressionISOAcsl3 (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in decreased expression of ACSL3 mRNAPMID:19684285 PMID:20005886 PMID:22539624 PMID:28213091 PMID:28922406
Acsl3multiple interactionsISOACSL3 (Homo sapiens)6480464CTD[Tetrachlorodibenzodioxin co-treated with Cycloheximide] affects the expression of ACSL3 mRNAPMID:19684285
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