A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID:
MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CCND1 protein]; [Tetrachlorodibenzodioxin binds to and results in increased activity of AHR protein] which results in decreased expression of CCND1 mRNA; AHR mutant form inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CCND1 protein]; AHR protein alternative form affects the reaction [Tetrachlorodibenzodioxin results in decreased expression of CCND1 mRNA]; resveratrol inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of CCND1 mRNA]; Tetrachlorodibenzodioxin inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased phosphorylation of CCND1 protein]; XAV939 inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CCND1 mRNA]; XAV939 inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CCND1 protein]
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CCND1 protein]; AHR protein affects the reaction [Tetrachlorodibenzodioxin results in increased expression of CCND1 protein]; Estradiol promotes the reaction [Tetrachlorodibenzodioxin promotes the reaction [CDKN1A protein binds to CCND1 protein]]; Tetrachlorodibenzodioxin inhibits the reaction [[AHR protein binds to CDK4 protein binds to CCND1 protein] which results in increased phosphorylation of RB1 protein]; Tetrachlorodibenzodioxin inhibits the reaction [Estradiol results in increased expression of CCND1 protein]; Tetrachlorodibenzodioxin promotes the reaction [CDKN1A protein binds to CCND1 protein]
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of CCND1 protein]; 3'-methoxy-4'-nitroflavone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of CCND1 protein]; [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CCND1 mRNA; [TIPARP gene mutant form results in increased susceptibility to Tetrachlorodibenzodioxin] which results in decreased expression of CCND1 mRNA; AHR protein inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CCND1 mRNA]; Tetrachlorodibenzodioxin inhibits the reaction [EGF protein results in increased expression of CCND1 protein]; Tetrachlorodibenzodioxin inhibits the reaction [IGF1 protein results in increased expression of CCND1 protein]; Tetrachlorodibenzodioxin inhibits the reaction [SHH protein results in increased expression of CCND1 protein]; Tetrachlorodibenzodioxin promotes the reaction [1,4-bis(2-(3,5-dichloropyridyloxy))benzene promotes the reaction [CDK4 protein binds to CCND1 protein]]; Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to CCND1 promoter]