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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 628802 Species: Rattus norvegicus RGD Object: Gene Symbol: Retsat Name: retinol saturase (all trans retinol 13,14 reductase)

Acc ID: CHEBI:28119 Term: 2,3,7,8-tetrachlorodibenzodioxine Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2. CasRN: 1746-01-6 Chemical ID: MESH:D013749

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
increases expression	ISO	RGD:731874	6480464	CTD	Tetrachlorodibenzodioxin results in increased expression of RETSAT mRNA	PMID:20106945
increases expression	ISO	RGD:731875	6480464	CTD	Tetrachlorodibenzodioxin results in increased expression of RETSAT mRNA	PMID:16960034
increases expression	EXP		6480464	CTD	Tetrachlorodibenzodioxin results in increased expression of RETSAT mRNA	PMID:15644576 PMID:18796159 PMID:16960034
increases expression	EXP		6480464	CTD	Tetrachlorodibenzodioxin results in increased expression of RETSAT mRNA	PMID:16960034 PMID:15644576 PMID:18796159
increases expression	EXP		6480464	CTD	Tetrachlorodibenzodioxin results in increased expression of RETSAT mRNA	PMID:18796159 PMID:16960034 PMID:15644576
increases expression	EXP		6480464	CTD	Tetrachlorodibenzodioxin results in increased expression of RETSAT mRNA	PMID:15644576 PMID:16960034 PMID:18796159
affects expression	ISO	RGD:731875	6480464	CTD	Tetrachlorodibenzodioxin affects the expression of RETSAT mRNA	PMID:21570461
increases expression	ISO	RGD:731874	6480464	CTD	Tetrachlorodibenzodioxin results in increased expression of RETSAT mRNA	PMID:20106945 PMID:21632981