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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 62188 Species: Mus musculus RGD Object: Gene Symbol: Dcn Name: decorin

Acc ID: CHEBI:28119 Term: 2,3,7,8-tetrachlorodibenzodioxine Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2. CasRN: 1746-01-6 Chemical ID: MESH:D013749

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
multiple interactions	ISO	RGD:1346102	6480464	CTD	Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of DCN mRNA]	PMID:11007951
decreases expression	ISO	RGD:1346102	6480464	CTD	Tetrachlorodibenzodioxin results in decreased expression of DCN mRNA	PMID:11007951
multiple interactions	EXP		6480464	CTD	AHR protein inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of DCN mRNA]	PMID:14728982
increases expression	EXP		6480464	CTD	Tetrachlorodibenzodioxin results in increased expression of DCN mRNA	PMID:14728982 PMID:16922920
increases expression	ISO	RGD:61895	6480464	CTD	Tetrachlorodibenzodioxin results in increased expression of DCN mRNA	PMID:15644576
increases expression	EXP		6480464	CTD	Tetrachlorodibenzodioxin results in increased expression of DCN mRNA	PMID:16922920 PMID:14728982
increases expression	ISO	RGD:1346102	6480464	CTD	Tetrachlorodibenzodioxin results in increased expression of DCN mRNA	PMID:21296121
affects expression	EXP		6480464	CTD	Tetrachlorodibenzodioxin affects the expression of DCN mRNA	PMID:21570461
decreases expression	ISO	RGD:1346102	6480464	CTD	Tetrachlorodibenzodioxin results in decreased expression of DCN mRNA	PMID:11007951 PMID:23152189