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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621693
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Aspa
Name: aspartoacylase
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Aspaaffects expressionEXP 6480464CTDTetrachlorodibenzodioxin affects the expression of ASPA mRNAPMID:22298810
Aspadecreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in decreased expression of ASPA mRNAPMID:33387578
Aspaaffects expressionISOASPA (Homo sapiens)6480464CTDTetrachlorodibenzodioxin affects the expression of ASPA mRNAPMID:22298810
Aspaaffects expressionISOAspa (Mus musculus)6480464CTDTetrachlorodibenzodioxin affects the expression of ASPA mRNAPMID:21570461 PMID:26377647
Aspamultiple interactionsISOAspa (Mus musculus)6480464CTDTetrachlorodibenzodioxin promotes the reaction [AHR protein binds to ASPA promoter]PMID:19654925
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