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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621229
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Glra3
Name: glycine receptor, alpha 3
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Glra3decreases expressionISOGLRA3 (Homo sapiens)6480464CTDTetrachlorodibenzodioxin results in decreased expression of GLRA3 mRNAPMID:19619570
Glra3multiple interactionsISOGLRA3 (Homo sapiens)6480464CTD[Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of GLRA3 mRNAPMID:19619570
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