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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620293
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ece1
Name: endothelin converting enzyme 1
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ece1affects expressionEXP 6480464CTDTetrachlorodibenzodioxin affects the expression of ECE1 mRNAPMID:22298810 PMID:34747641
Ece1decreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in decreased expression of ECE1 mRNAPMID:18796159 PMID:20959002 PMID:21215274
Ece1affects expressionISOEce1 (Mus musculus)6480464CTDTetrachlorodibenzodioxin affects the expression of ECE1 mRNAPMID:21570461
Ece1increases expressionISOEce1 (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in increased expression of ECE1 mRNAPMID:20819909
Ece1multiple interactionsISOEce1 (Mus musculus)6480464CTDTetrachlorodibenzodioxin promotes the reaction [AHR protein binds to ECE1 gene]PMID:20819909
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