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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 61867
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Casp9
Name: caspase 9
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Casp9affects expressionEXP 6480464CTDTetrachlorodibenzodioxin affects the expression of CASP9 mRNAPMID:22298810
Casp9increases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in increased expression of CASP9 mRNAPMID:19520675 PMID:33387578
Casp9affects expressionISOCasp9 (Mus musculus)6480464CTDTetrachlorodibenzodioxin affects the expression of CASP9 mRNAPMID:21570461
Casp9decreases expressionISOCASP9 (Homo sapiens)6480464CTDTetrachlorodibenzodioxin results in decreased expression of CASP9 mRNAPMID:23152189
Casp9increases expressionISOCasp9 (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in increased expression of CASP9 mRNA; Tetrachlorodibenzodioxin results in increased expression of CASP9 proteinPMID:15667827 PMID:15972635
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