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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3344
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Plcb1
Name: phospholipase C beta 1
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Plcb1affects expressionEXP 6480464CTDTetrachlorodibenzodioxin affects the expression of PLCB1 mRNAPMID:22298810 PMID:32109520
Plcb1decreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in decreased expression of PLCB1 mRNAPMID:21215274
Plcb1increases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in increased expression of PLCB1 mRNAPMID:34747641
Plcb1affects expressionISOPlcb1 (Mus musculus)6480464CTDTetrachlorodibenzodioxin affects the expression of PLCB1 mRNAPMID:21570461 PMID:26377647
Plcb1decreases expressionISOPLCB1 (Homo sapiens)6480464CTDTetrachlorodibenzodioxin results in decreased expression of PLCB1 mRNAPMID:17101203
Plcb1decreases expressionISOPlcb1 (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in decreased expression of PLCB1 mRNAPMID:26290441
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