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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2599
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Fcer1g
Name: Fc epsilon receptor Ig
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Fcer1gaffects expressionEXP 6480464CTDTetrachlorodibenzodioxin affects the expression of FCER1G mRNAPMID:34747641
Fcer1gaffects expressionISOFcer1g (Mus musculus)6480464CTDTetrachlorodibenzodioxin affects the expression of FCER1G mRNAPMID:21570461 PMID:24680724 PMID:28922406
Fcer1gincreases expressionISOFcer1g (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in increased expression of FCER1G mRNAPMID:21041162
Fcer1gmultiple interactionsISOFcer1g (Mus musculus)6480464CTD[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of FCER1G mRNA; [TIPARP gene mutant form results in increased susceptibility to Tetrachlorodibenzodioxin] which results in decreased expression of FCER1G mRNAPMID:17942748 PMID:25975270
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