A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID:
MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
[Diethylnitrosamine co-treated with Tetrachlorodibenzodioxin] results in decreased expression of EGFR protein; geldanamycin inhibits the reaction [Tetrachlorodibenzodioxin inhibits the reaction [EGF protein binds to EGFR protein]]; Tetrachlorodibenzodioxin inhibits the reaction [EGF protein binds to EGFR protein]; Tetrachlorodibenzodioxin results in decreased expression of and affects the localization of EGFR protein
CSK protein promotes the reaction [Tetrachlorodibenzodioxin inhibits the reaction [EGF protein binds to EGFR protein]]; geldanamycin inhibits the reaction [Tetrachlorodibenzodioxin inhibits the reaction [EGF protein binds to EGFR protein]]; Tetrachlorodibenzodioxin inhibits the reaction [EGF protein binds to EGFR protein]
[Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of EGFR mRNA; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased phosphorylation of and results in increased activity of EGFR protein]; EGFR protein promotes the reaction [Tetrachlorodibenzodioxin results in increased phosphorylation of and results in increased activity of AKT1 protein]; EGFR protein promotes the reaction [Tetrachlorodibenzodioxin results in increased phosphorylation of and results in increased activity of MAPK1 protein]; EGFR protein promotes the reaction [Tetrachlorodibenzodioxin results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Tetrachlorodibenzodioxin inhibits the reaction [EGF protein binds to EGFR protein]; Tetrachlorodibenzodioxin results in increased phosphorylation of and results in increased activity of EGFR protein
