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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2200
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bcl2l1
Name: Bcl2-like 1
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Bcl2l1affects expressionEXP 6480464CTDTetrachlorodibenzodioxin affects the expression of BCL2L1 mRNAPMID:34747641
Bcl2l1decreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in decreased expression of BCL2L1 mRNA; Tetrachlorodibenzodioxin results in decreased expression of BCL2L1 proteinPMID:15965093 PMID:32109520
Bcl2l1increases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in increased expression of BCL2L1 mRNA; Tetrachlorodibenzodioxin results in increased expression of BCL2L1 proteinPMID:15965093
Bcl2l1affects expressionISOBcl2l1 (Mus musculus)6480464CTDTetrachlorodibenzodioxin affects the expression of BCL2L1 mRNAPMID:21570461 PMID:24680724
Bcl2l1affects expressionISOBCL2L1 (Homo sapiens)6480464CTDTetrachlorodibenzodioxin affects the expression of BCL2L1 mRNAPMID:22574217
Bcl2l1decreases expressionISOBcl2l1 (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in decreased expression of BCL2L1 mRNAPMID:19933214
Bcl2l1decreases expressionISOBCL2L1 (Homo sapiens)6480464CTDTetrachlorodibenzodioxin results in decreased expression of BCL2L1 mRNAPMID:16039398
Bcl2l1increases expressionISOBcl2l1 (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in increased expression of BCL2L1 mRNAPMID:12167310 PMID:14718646
Bcl2l1multiple interactionsISOBcl2l1 (Mus musculus)6480464CTD[TIPARP gene mutant form results in increased susceptibility to Tetrachlorodibenzodioxin] which results in decreased expression of BCL2L1 mRNAPMID:25975270
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