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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2034
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Adcy4
Name: adenylate cyclase 4
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Adcy4increases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in increased expression of ADCY4 mRNAPMID:20959002 PMID:33387578 PMID:34747641
Adcy4affects expressionISOAdcy4 (Mus musculus)6480464CTDTetrachlorodibenzodioxin affects the expression of ADCY4 mRNAPMID:26377647
Adcy4increases expressionISOADCY4 (Homo sapiens)6480464CTDTetrachlorodibenzodioxin results in increased expression of ADCY4 mRNAPMID:19684285
Adcy4multiple interactionsISOAdcy4 (Mus musculus)6480464CTD[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of ADCY4 mRNAPMID:17942748
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