• View As List
• View As Table

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1349804 Species: Homo sapiens RGD Object: Gene Symbol: ACVR1B Name: activin A receptor, type IB

Acc ID: CHEBI:28119 Term: 2,3,7,8-tetrachlorodibenzodioxine Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2. CasRN: 1746-01-6 Chemical ID: MESH:D013749

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
decreases expression	ISO	RGD:1332207	6480464	CTD	Tetrachlorodibenzodioxin results in decreased expression of ACVR1B mRNA	PMID:19465110
multiple interactions	ISO	RGD:1332207	6480464	CTD	[Tetrachlorodibenzodioxin co-treated with Lipopolysaccharides] results in increased methylation of ACVR1B gene	PMID:21212295
affects expression	ISO	RGD:735207	6480464	CTD	Tetrachlorodibenzodioxin affects the expression of ACVR1B mRNA	PMID:22298810