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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1318133 Species: Mus musculus RGD Object: Gene Symbol: Mzf1 Name: myeloid zinc finger 1

Acc ID: CHEBI:28119 Term: 2,3,7,8-tetrachlorodibenzodioxine Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2. CasRN: 1746-01-6 Chemical ID: MESH:D013749

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
increases expression	ISO	RGD:1318132	6480464	CTD	Tetrachlorodibenzodioxin results in increased expression of MZF1 mRNA	PMID:12377990 PMID:15345368
increases expression	ISO	RGD:1318132	6480464	CTD	Tetrachlorodibenzodioxin results in increased expression of MZF1 mRNA	PMID:15345368 PMID:12377990
multiple interactions	EXP		6480464	CTD	Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to MZF1 promoter]	PMID:19654925
affects expression	EXP		6480464	CTD	Tetrachlorodibenzodioxin affects the expression of MZF1 mRNA	PMID:21570461