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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2605 Species: Rattus norvegicus RGD Object: Gene Symbol: Fgf1 Name: fibroblast growth factor 1 (acidic)

Acc ID: CHEBI:28112 Term: nickel atom Definition: Chemical element with atomic number 28. CasRN: 7440-02-0 Chemical ID: MESH:D009532

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
decreases expression	EXP		6480464	CTD	Nickel results in decreased expression of FGF1 mRNA	PMID:19130878
decreases expression	ISO	RGD:10577	6480464	CTD	Nickel results in decreased expression of FGF1 mRNA	PMID:12540486