• View As List
• View As Table

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 62102 Species: Mus musculus RGD Object: Gene Symbol: Ctsk Name: cathepsin K

Acc ID: CHEBI:28088 Term: genistein Definition: A member of the class of 7-hydroxyisoflavones that is 7-hydroxyisoflavone with additional hydroxy groups at positions 5 and 4'. It is a phytoestrogenic isoflavone with antioxidant properties. CasRN: 446-72-0 Chemical ID: MESH:D019833

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
affects expression	EXP		6480464	CTD	Genistein affects the expression of CTSK mRNA	PMID:17166402
decreases expression	EXP		6480464	CTD	Genistein results in decreased expression of CTSK mRNA	PMID:17295206
multiple interactions	EXP		6480464	CTD	[CSF1 protein co-treated with TNFSF11 protein co-treated with Genistein] results in decreased expression of CTSK mRNA Genistein promotes the reaction [[CSF1 protein co-treated with TNFSF11 protein co-treated with Zinc Sulfate] results in decreased expression of CTSK mRNA] Zinc Sulfate promotes the reaction [[CSF1 protein co-treated with TNFSF11 protein co-treated with Genistein] results in decreased expression of CTSK mRNA] Zinc Sulfate promotes the reaction [Genistein results in decreased expression of CTSK mRNA]	PMID:17295206