GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ugt1a1 | decreases activity | ISO | UGT1A1 (Homo sapiens) | 6480464 | CTD | Genistein results in decreased activity of UGT1A1 protein | PMID:16051636 | Ugt1a1 | decreases expression | ISO | UGT1A1 (Homo sapiens) | 6480464 | CTD | Genistein results in decreased expression of UGT1A1 mRNA; Genistein results in decreased expression of UGT1A1 protein | PMID:18634814 | Ugt1a1 | increases glucuronidation | ISO | UGT1A1 (Homo sapiens) | 6480464 | CTD | UGT1A1 protein results in increased glucuronidation of Genistein | PMID:14557274 PMID:15988124 | Ugt1a1 | multiple interactions | ISO | Ugt1a1 (Mus musculus) | 6480464 | CTD | Genistein inhibits the reaction [Acetaminophen results in decreased expression of UGT1A1 mRNA] | PMID:23333575 | |
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