GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Atm | affects response to substance | ISO | Atm (Mus musculus) | 6480464 | CTD | ATM protein affects the susceptibility to Genistein | PMID:21177254 | Atm | increases phosphorylation | ISO | ATM (Homo sapiens) | 6480464 | CTD | Genistein results in increased phosphorylation of ATM protein | PMID:15177039 PMID:19038232 | Atm | multiple interactions | ISO | ATM (Homo sapiens) | 6480464 | CTD | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Genistein results in increased phosphorylation of ATM protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Genistein results in increased phosphorylation of ATM protein]; ATM protein affects the reaction [Genistein results in increased expression of and results in increased phosphorylation of TP53 protein]; ATM protein affects the reaction [Genistein results in increased phosphorylation of H2AX protein]; Caffeine inhibits the reaction [Genistein results in increased phosphorylation of ATM protein]; U 0126 inhibits the reaction [Genistein results in increased phosphorylation of ATM protein] | PMID:15177039 PMID:19038232 | | ||||||||||||||||||||||
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