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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 727889
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Rela
Name: RELA proto-oncogene, NF-kB subunit
Acc ID: CHEBI:28061
Term: alpha-D-galactose
Definition: D-Galactopyranose having alpha-configuration at the anomeric centre.
Chemical ID: MESH:D005690
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Relaaffects localizationISORELA (Homo sapiens)6480464CTDGalactose affects the localization of RELA proteinPMID:29412148
Relaincreases expressionISORela (Mus musculus)6480464CTDGalactose results in increased expression of RELA mRNA; Galactose results in increased expression of RELA proteinPMID:22687555
Relamultiple interactionsISORELA (Homo sapiens)6480464CTDginsenoside F1 inhibits the reaction [Galactose affects the localization of RELA protein]; SB 203580 inhibits the reaction [Galactose affects the localization of RELA protein]PMID:29412148
Relamultiple interactionsISORela (Mus musculus)6480464CTD[Galactose co-treated with Aluminum Chloride] results in increased expression of and results in increased phosphorylation of RELA protein; [Galactose co-treated with lipopolysaccharide, Escherichia coli O111 B4] affects the localization of and results in increased expression of RELA protein; astragalin inhibits the reaction [[Galactose co-treated with Aluminum Chloride] results in increased expression of and results in increased phosphorylation of RELA protein]; Estradiol inhibits the reaction [[Galactose co-treated with Aluminum Chloride] results in increased expression of and results in increased phosphorylation of RELA protein]; Galactose results in increased expression of and results in increased activity of RELA protein; protocatechuic acid inhibits the reaction [Galactose results in increased expression of and results in increased activity of RELA protein]; protocatechuic acid inhibits the reaction [Galactose results in increased expression of RELA mRNA]; protocatechuic acid inhibits the reaction [Galactose results in increased expression of RELA protein]; scoparone inhibits the reaction [[Galactose co-treated with lipopolysaccharide, Escherichia coli O111 B4] affects the localization of and results in increased expression of RELA protein]PMID:22687555 PMID:23535186 PMID:35537655
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