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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731027 Species: Homo sapiens RGD Object: Gene Symbol: BDNF Name: brain-derived neurotrophic factor

Acc ID: CHEBI:28051 Term: veratridine Definition: A steroid that has formula C36H51NO11. CasRN: 71-62-5 Chemical ID: MESH:D014701

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
multiple interactions	ISO	RGD:10235	6480464	CTD	cypermethrin inhibits the reaction [Veratridine results in increased expression of BDNF mRNA] Permethrin inhibits the reaction [Veratridine results in increased expression of BDNF mRNA]	PMID:11082455
increases expression	ISO	RGD:10235	6480464	CTD	Veratridine results in increased expression of BDNF mRNA	PMID:11082455
multiple interactions	ISO	RGD:2202	6480464	CTD	Tetrodotoxin inhibits the reaction [Veratridine results in increased expression of BDNF mRNA]	PMID:16166269
increases expression	ISO	RGD:2202	6480464	CTD	Veratridine results in increased expression of BDNF mRNA	PMID:16166269