GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731577
Species: Homo sapiens
RGD Object: Gene
Symbol: FBN1
Name: fibrillin 1
Acc ID: CHEBI:28001
Term: vancomycin
Definition: A complex glycopeptide from Streptomyces orientalis. It inhibits a specific step in the synthesis of the peptidoglycan layer in the Gram-positive bacteria Staphylococcus aureus and Clostridium difficile.
CasRN: 1404-90-6
Chemical ID: MESH:D014640
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionISORGD:7315786480464CTDVancomycin results in decreased expression of FBN1 mRNA

PMID:18930951
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