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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1552280 Species: Mus musculus RGD Object: Gene Symbol: Nefl Name: neurofilament, light polypeptide

Acc ID: CHEBI:27958 Term: cocaine Definition: A tropane alkaloid obtained from leaves of the South American shrub Erythroxylon coca. CasRN: 50-36-2 Chemical ID: MESH:D003042

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
affects expression	ISO	RGD:621458	6480464	CTD	Cocaine affects the expression of NEFL mRNA	PMID:20187946
decreases expression	ISO	RGD:621458	6480464	CTD	Cocaine results in decreased expression of NEFL mRNA	PMID:16076954
decreases expression	ISO	RGD:1344238	6480464	CTD	Cocaine results in decreased expression of NEFL mRNA	PMID:12629581