GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732280
Species: Mus musculus
RGD Object: Gene
Symbol: Ccr1
Name: chemokine (C-C motif) receptor 1
Acc ID: CHEBI:27899
Term: cisplatin
Definition: A platinum-containing anticancer drug that interacts with, and forms cross-links between, DNA and proteins. It is used as a neoplasm inhibitor to treat solid tumours, primarily of the testis and ovary.
CasRN: 15663-27-1
Chemical ID: MESH:D002945
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionEXP 6480464CTDCisplatin results in increased expression of CCR1 mRNA

PMID:15814532
multiple interactionsEXP 6480464CTDpirinixic acid inhibits the reaction [Cisplatin results in increased expression of CCR1 mRNA]

PMID:15814532
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