GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Hdac2 | increases expression | EXP | | 6480464 | CTD | Lead results in increased expression of HDAC2 mRNA; Lead results in increased expression of HDAC2 protein | PMID:29301062 | Hdac2 | multiple interactions | EXP | | 6480464 | CTD | [HDAC1 protein co-treated with HDAC2 protein] inhibits the reaction [Lead results in decreased expression of NOTCH2 protein]; EZH2 protein inhibits the reaction [Lead results in increased expression of HDAC2 mRNA]; EZH2 protein inhibits the reaction [Lead results in increased expression of HDAC2 protein]; Lead promotes the reaction [HDAC1 protein binds to HDAC2 protein] | PMID:29301062 | Hdac2 | affects expression | ISO | HDAC2 (Homo sapiens) | 6480464 | CTD | Lead affects the expression of HDAC2 mRNA | PMID:28903495 | | ||||||||||||||||||||||
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