GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Gfap | affects expression | ISO | GFAP (Homo sapiens) | 6480464 | CTD | Lead affects the expression of GFAP mRNA | PMID:28903495 | Gfap | increases expression | ISO | Gfap (Mus musculus) | 6480464 | CTD | Lead results in increased expression of GFAP mRNA; Lead results in increased expression of GFAP protein | PMID:34742682 | Gfap | increases expression | ISO | GFAP (Homo sapiens) | 6480464 | CTD | Lead results in increased expression of GFAP protein | PMID:34165617 | Gfap | multiple interactions | ISO | Gfap (Mus musculus) | 6480464 | CTD | Dietary Fats promotes the reaction [Lead results in increased expression of GFAP mRNA]; Dietary Fats promotes the reaction [Lead results in increased expression of GFAP protein]; Lead promotes the reaction [Dietary Fats results in increased expression of GFAP mRNA]; Lead promotes the reaction [Dietary Fats results in increased expression of GFAP protein]; Tretinoin inhibits the reaction [Dietary Fats promotes the reaction [Lead results in increased expression of GFAP protein]]; Tretinoin inhibits the reaction [Lead promotes the reaction [Dietary Fats results in increased expression of GFAP protein]] | PMID:34742682 | Gfap | multiple interactions | ISO | GFAP (Homo sapiens) | 6480464 | CTD | N,N'-Bis(2-mercaptoethyl)isophthalamide inhibits the reaction [Lead results in increased expression of GFAP protein] | PMID:34165617 | |
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