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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2074
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ahr
Name: aryl hydrocarbon receptor
Acc ID: CHEBI:27889
Term: lead(0)
Definition: An elemental lead that has formula Pb.
Chemical ID: MESH:D007854
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ahraffects expressionEXP 6480464CTDLead affects the expression of AHR mRNAPMID:23631153
Ahrmultiple interactionsISOAhr (Mus musculus)6480464CTDAHR protein promotes the reaction [Lead results in increased activity of CRYZ protein]; AHR protein promotes the reaction [Lead results in increased activity of GSTA2 protein]; Lead results in increased activity of [AHR protein binds to ARNT protein]PMID:15297030 PMID:16093525
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