GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Nampt | increases activity | ISO | NAMPT (Homo sapiens) | 6480464 | CTD | resveratrol results in increased activity of NAMPT protein | PMID:24603648 | Nampt | increases expression | ISO | Nampt (Mus musculus) | 6480464 | CTD | resveratrol metabolite results in increased expression of NAMPT mRNA; resveratrol results in increased expression of NAMPT mRNA | PMID:23717508 | Nampt | increases expression | ISO | NAMPT (Homo sapiens) | 6480464 | CTD | resveratrol results in increased expression of NAMPT mRNA | PMID:24603648 | Nampt | multiple interactions | ISO | Nampt (Mus musculus) | 6480464 | CTD | resveratrol inhibits the reaction [MIR34A mRNA inhibits the reaction [NAMPT protein results in increased chemical synthesis of NAD]] | PMID:23834033 | Nampt | multiple interactions | ISO | NAMPT (Homo sapiens) | 6480464 | CTD | 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [resveratrol results in increased activity of NAMPT protein]; PARP1 protein affects the reaction [resveratrol results in increased expression of NAMPT protein]; resveratrol results in decreased activity of and results in increased secretion of NAMPT protein; resveratrol results in increased acetylation of and results in increased expression of NAMPT protein; SIRT1 protein inhibits the reaction [resveratrol results in increased secretion of NAMPT protein]; STF-118804 inhibits the reaction [resveratrol results in increased expression of NAMPT protein] | PMID:24603648 PMID:25533949 | | ||||||||||||||||||||||
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