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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620917
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Pik3cb
Name: phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
Acc ID: CHEBI:27881
Term: resveratrol
Definition: A stilbenol that is stilbene in which the phenyl groups are substituted at positions 3, 5, and 4' by hydroxy groups.
Chemical ID: MESH:C059514
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pik3cbmultiple interactionsEXP 6480464CTDresveratrol inhibits the reaction [Streptozocin results in decreased expression of PIK3CB mRNA]PMID:26071184
Pik3cbdecreases expressionISOPIK3CB (Homo sapiens)6480464CTDresveratrol results in decreased expression of PIK3CB mRNAPMID:25667456
Pik3cbmultiple interactionsISOPIK3CB (Homo sapiens)6480464CTDresveratrol results in decreased activity of [PIK3R1 protein binds to PIK3CB protein]PMID:17550345
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