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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620416
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Dnm1l
Name: dynamin 1-like
Acc ID: CHEBI:27881
Term: resveratrol
Definition: A stilbenol that is stilbene in which the phenyl groups are substituted at positions 3, 5, and 4' by hydroxy groups.
Chemical ID: MESH:C059514
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Dnm1lmultiple interactionsEXP 6480464CTDresveratrol inhibits the reaction [Rotenone results in decreased expression of DNM1L mRNA]; resveratrol inhibits the reaction [Rotenone results in decreased expression of DNM1L protein]PMID:26770656
Dnm1lmultiple interactionsISODNM1L (Homo sapiens)6480464CTD[Plant Extracts co-treated with Resveratrol] results in increased expression of DNM1L mRNAPMID:23557933
Dnm1lmultiple interactionsISODnm1l (Mus musculus)6480464CTD6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [Resveratrol inhibits the reaction [manganese chloride promotes the reaction [PPARGC1A protein binds to DNM1L promoter]]]; 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [Resveratrol inhibits the reaction [manganese chloride results in increased expression of DNM1L mRNA]]; 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [Resveratrol inhibits the reaction [manganese chloride results in increased expression of DNM1L protein]]; Resveratrol inhibits the reaction [manganese chloride promotes the reaction [PPARGC1A protein binds to DNM1L promoter]]; Resveratrol inhibits the reaction [manganese chloride results in increased expression of DNM1L mRNA]; Resveratrol inhibits the reaction [manganese chloride results in increased expression of DNM1L protein]PMID:34738708
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